Laboratório de Biologia Integrativa e Sistêmica

O LaBIS foi fundado em Junho de 2014 e está localizado no Centro de Biologia Molecular e Engenharia Genética (CBMEG) da UNICAMP.
O foco principal do nosso grupo é entender as intricadas interações envolvidas na biologia de sistema de organismos com interesse econômico, indo da fermentação promovida por fungos e bactérias para produção de bioprodutos até a digestão dos insetos praga da agricultura. Para tanto, todos nossos projetos utilizam abordagens clássicas de biologia computacional e bioinformática, somadas ao emprego de métodologias de análises de grande volume de dados voltadas para Biologia Molecular, visando a integração de diferentes fontes de informação.

Publicações recentes

Pathogenic bacteria in the aquatic environment surrounding pig farms and cities: a microbiome analysis from Paraná and Santa Catarina, Brazil

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Differential gene expression toward species of Aristolochia impairing the performance of the Troidini butterfly Battus polydamas

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Metabarcoding analysis reveals an interaction among distinct groups of bacteria associated with three different varietals of grapes used for wine production in Brazil

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Comparison of bacterial diversity in wet- and dry-aged beef using traditional microbiology and next generation sequencing

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Multi-omics network model reveals key genes associated with p-coumaric acid stress response in an industrial yeast strain

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Transcriptome analysis of host-specific interactions in natural populations of the cotton bollworm (Helicoverpa armigera)

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Mitogenome reveals high levels of differentiation and structure among populations of the emblematic Amazonian white sand specialist butterfly Heliconius hermathena

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The Spruce Budworm Genome: Reconstructing the Evolutionary History of Antifreeze Proteins

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Mechanisms behind polyphagia in a pest insect: Responses of Spodoptera frugiperda (J.E. Smith) strains to preferential and alternative larval host plants assessed with gene regulatory networks

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Interactomes: Experimental and In Silico Approaches

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Probabilistic Graphical Models Applied to Biological Networks

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New germline GATA1 variant in females with anemia and thrombocytopenia

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Transcript expression plasticity as a response to alternative larval host plants in the speciation process of corn and rice strains of Spodoptera frugiperda

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Transcriptome differential co-expression reveals distinct molecular response of fall-armyworm strains to DIMBOA

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Assessment of ethanol tolerance of Kluyveromyces marxianus CCT 7735 selected by adaptive laboratory evolution

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The roles of hybridization and habitat fragmentation in the evolution of Brazil’s enigmatic longwing butterflies, Heliconius nattereri and H. hermathena

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